PREMIER Biosoft International today announced the world wide release of version 5 of AlleleID®
AlleleID®, which helps design microarrays and real time PCR diagnostic assays for pathogen detection or bacterial identification will now help MLPA® users design custom MLPA® probes.
Palo Alto, California--May 30, 2007, PREMIER Biosoft International today announced the world wide release of version 5 of AlleleID®, the only tool available for designing diagnostic assays for both real time PCR and microarrays. AlleleID® now includes support for designing custom probes for MLPA® assays. AlleleID® will help MLPA® users design custom oligos for genes that do not have kits available.
Multiplex Ligation-dependent Probe Amplification (MLPA®)
is a method to establish the copy number of up to 45
nucleic acid sequences in a single reaction. MLPA®
probes are able to discriminate between sequences that
differ by just one nucleotide, making them a highly
sensitive and precise tool for detecting the changes.
Current efforts are directed towards more comprehensive
cataloging and characterization of such changes.
For design support, the company has teamed up with MRC-Holland,
the inventors of MLPA® technology. "With this
collaboration, both PREMIER Biosoft and MRC-Holland
will use their core competencies and expertise to develop
a powerful bioinformatics tool for MLPA® users."
commented Kay Brown, V.P. Business Development and Marketing.
AlleleID® is a comprehensive desktop tool designed to
address the challenges of pathogen detection, bacterial
identification or taxa/species discrimination using
microarrays and TaqMan® TaqMan® MGB, SYBR®
Green and molecular beacon qPCR assays. With ClustalW
multiple sequence alignment at its core, AlleleID® can
design species specific/cross species probes for microarrays
or TaqMan®, TaqMan® MGB, SYBR® Green and
molecular beacon qPCR assays.
AlleleID® employs a sophisticated algorithm to assure
assay success. Highly specific oligos are designed by
avoiding regions of significant homology found by automatically
interpreting BLAST search results. The oligos designed
can be BLAST searched, to verify their specificity.
Primer efficiency is enhanced by automatically avoiding
template secondary structures.
For details, please visit: http://www.premierbiosoft.com/bacterial-identification/index.html
About PREMIER Biosoft International:
Founded in 1994, the company is a group of computer scientists and molecular biologists dedicated to producing cutting edge intuitive software for the molecular biologist. The goal of the company is to study the most recent innovations in molecular biology and translate them into software products that aid biologists. Additional information about PREMIER Biosoft International can be found at http://www.premierbiosoft.com
PREMIER Biosoft International