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PREMIER Biosoft Announces the Release of SimLipid® 6.03 Facilitating Large-Scale Lipidomics Analysis Using High-Resolution Mass Spectrometers

Palo Alto, California -- March 14, 2018, PREMIER Biosoft today announced the release of SimLipid 6.03. The new version is designed to facilitate large-scale lipidomics analysis using data generated by High-Resolution Mass Spectrometers (HRMS) - FT-ICR, Orbitrap and time of flight (TOF) analyzers based Mass Spectrometers – with mass accuracy below 5 ppm. HRMS provides several advantages in lipidomics studies, including high resolving power, increased mass accuracy and increased limits of detection.

SimLipid 6.03 enables high-resolution mass spectrometry lipidomic data analysis by faster raw data pre-processing and by using an efficient search engine for speedy database searches, resulting in an increased throughput. The key features included are:

  • Raw data or spectra list import from 2,000,000 scans/peaklists at a click of a button.
  • Experimental design modeling for HRMS based lipidomics analysis that involves MS1 data averaging and alignment of m/z peaks across biological and technical replicates.
  • Database searches for up to 100,000 MS or MS/MS scans at a time in batch mode.
  • Lipid fingerprinting with greater accuracy by annotating the lipid species that were identified with high confidence using product ion data from tandem MS spectra.
  • Multiple report layouts and filter criteria to export analysis results for Data Dependent Acquisition (DDA) and Data Independent Acquisition (DIA) tandem MS based lipidomic data analysis.

"The large datasets generated by HRMS based lipidomics workflows increase the time for data pre-processing, identification and further downstream analysis. There is a need for a robust post data acquisition software to convert the enormous raw mass spectral data into meaningful information" said Arun Apte, CEO at PREMIER Biosoft. "SimLipid 6.03, with its efficient data processing, will enable researchers to achieve accurate lipid identification, quantitation, and further comparative analysis of lipid species across biological samples not only quickly but more accurately."

For details, please visit: http://www.premierbiosoft.com/products/upgrades/sl_upgrades.html.

About PREMIER Biosoft International:
Founded in 1994, is a group of computer scientists and biologists dedicated to producing cutting edge intuitive software for research in life sciences. Our goal is to study the most recent innovations in life sciences and translate them into software products to aid research.

More information is available at: http://www.premierbiosoft.com.

Himani Gupta
Email: support@premierbiosoft.com

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